Eight children in the UK have been saved from severe inherited diseases due to a new three-person in vitro fertilisation (IVF) technique, as reported by scientists from Newcastle University. The method, which is currently prohibited in the United States, involves transferring parts from inside the mother’s fertilised egg, i.e., its nucleus, along with the nucleus of the father’s sperm, into a healthy egg provided by an anonymous donor. This process prevents the transmission of mutated genes from within the mother’s mitochondria that could result in incurable and potentially fatal disorders. This breakthrough marks the result of years of work encompassing scientific and technical challenges, ethical inquiry, public and patient engagement, law-making, regulatory drafting and execution, and the establishment of a system for monitoring and caring for the mothers and infants.